Basic Information
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Product
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Hyaluronic acid
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Chemical
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Sodium Hyaluronate
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Cas
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9004-61-9
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MF
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C14H22NNaO11
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MW
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403.31
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Appearance
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White powder
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Assay
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50000Da
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Package
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1Kg/Foil Bag or 25Kg/Drum or As per your request
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Storage
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Store in cool and dry places, keep away from strong light
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Shelf life
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2 years when properly stored
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Mechanism of action
1) Percutaneous absorption
Skin model was used to test the percutaneous absorption of hydrolyzed sodium hyaluronate. The results showed that the percutaneous absorption rate of hydrolyzed sodium hyaluronate reached 36.2 % in 1 hour, 60.7 % in 8 hours and 69.5 % in 24 hours.
2) Scavenging free radicals
Hydrolyzed sodium hyaluronate can effectively eliminate reactive oxygen free radicals ( ROS ) induced by ultraviolet radiation, enhance cell antioxidant capacity and enhance skin's defense against ultraviolet radiation.
3) Repair damaged cells
hydrolyzed sodium hyaluronate can repair damaged cells and improve cell activity, thus reducing the damage of external environment to skin cells.
Specification
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Items
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Specifications
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Cosmetic grade
sodium hyaluroate
(Lowest Molecular Weight )
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Cosmetic grade
sodium hyaluroate
(Low Molecular Weight )
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Cosmetic grade sodium hyaluroate
(Middle Molecular Weight )
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Cosmetic grade
sodium hyaluroate
(High Molecular Weight )
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|
Description
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White powder
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White powder
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White powder
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White powder
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|
Particle size
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100% pass through 80 mesh
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100% pass through 80 mesh
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100% pass through 80 mesh
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100% pass through 80 mesh
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|
PH
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5.0-8.5
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5.0-8.5
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5.0-8.5
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5.0-8.5
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Transparency
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≥99.0%
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≥99.0%
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≥99.0%
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≥99.0%
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Molecular Weight
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2,000 Da - 8,000 Da
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8,000 Da - 50,000 Da
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1.0-1.5M Da.
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≥1.8M Da
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|
Loss on drying
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≤8.0%
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≤8.0%
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≤8.0%
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≤8.0%
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Bulk Density
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0.10-0.60g/cm3
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0.10-0.60g/cm3
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0.10-0.60g/cm3
|
0.10-0.60g/cm3
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Protein
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≤0.05%
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≤0.05%
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≤0.05%
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≤0.05%
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Heavy metals
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≤10ppm
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≤10ppm
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≤10ppm
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≤10ppm
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Arsenic
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≤2ppm
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≤2ppm
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≤2ppm
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≤2ppm
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Glucuronic acid
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≥44%
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≥44%
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≥44%
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≥44%
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Sodium Hyaluronate
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≥95%
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≥95%
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≥95%
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≥95%
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Bacteria counts
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≤100cfu/g
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≤100cfu/g
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≤100cfu/g
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≤100cfu/g
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Mold & Yeast
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≤10cfu/g
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≤10cfu/g
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≤10cfu/g
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≤10cfu/g
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E.Coli
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Negative
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Negative
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Negative
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Negative
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S.Aureus
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Negative
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Negative
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Negative
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Negative
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S.Apecies
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Negative
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Negative
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Negative
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Negative
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Main efficacy
1) Deep moisturizing
Hydrolyzed sodium hyaluronate can be absorbed through skin, deeply moisturize skin, and increase skin moisture content. It can be used together with macromolecular sodium hyaluronate to achieve synergistic effect and better moisturizing effect.
2) Fade wrinkles
After 15 days, 30 days and 60 days of use, the average wrinkle depth ( sa ) of the hydrolyzed sodium hyaluronate group decreased by 16.0 %, 20.3 % and 25.6 % respectively.
3) Increase skin elasticity
Skin elasticity of the hydrolyzed sodium hyaluronate group increased 4.6 %, 5.2 % and 6.1 % respectively after 15 days, 30 days and 60 days of use. Long - term use of hydrolyzed sodium hyaluronate makes skin firm and elastic.
4) Clinical research
Dermatologists judge that after 30 days of use, 40 % of the subjects had significantly improved their wrinkles, while after 60 days of use, 60 % of the subjects had significantly reduced their wrinkles.