Different kinds of Silica/Silico Dioxide

Gel-method silicon dioxide has become the first choice for high-end excipients in the pharmaceutical field due to its high purity and regular pore structure, and its production process and performance are significantly better than traditional precipitation-method products. The gel method is formed by sol-gel conversion under acidic conditions, with smaller primary particle size (<20nm), specific surface area up to 200-1000m²/g, uniform pore distribution, and general purity ≥99.5%, while precipitation-method products mostly have a purity of 95%-98% and a wide pore distribution.

In medicinal scenarios, gel-method products are mainly used in two major fields: first, as a drug carrier, its porous structure can load active ingredients such as vitamins and probiotics, protect them from gastric acid erosion. For example, when used in vitamin C preparations, it can increase the bioavailability by 30%; second, as a sustained and controlled release excipient, it controls the drug release rate by adjusting the pore size. For example, in nifedipine sustained-release tablets, it can achieve 12-hour uniform drug release.

Qingdao healthchem Biotech Co.,Ltd can supply high-end food grade Silicon Dioxide, feel free to contact us for more information:  sales@healthchembio.com